Across TCGA cell cohorts, C2orf72 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C2orf72-associated genes across cancer lineages are PRAMEF9, LCE1F, and RBMY1E. Each is linked with C2orf72 in more than 1 cancer types. Because this analysis shows association rather than direction, both C2orf72-to-partner and partner-to-C2orf72 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf72→partner) and Y-score (partner→C2orf72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PRAMEF9 →	+0.005	+5.022	<.001	.002	3	1
LARGE_INTESTINE	LCE1F →	+0.122	+4.415	<.001	.007	3	1
LARGE_INTESTINE	RBMY1E →	+0.055	+5.022	<.001	.002	3	1
LARGE_INTESTINE	CCL23 →	+0.387	+4.930	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

C2orf72 survival (RNA) · tumor vs normal (RNA) · all C2orf72 data types