C2orf69

Across TCGA patient cohorts, C2orf69 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,084 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C2orf69-associated proteins across cancer lineages are ORC3, SPAST, and NCAPD2. Each is linked with C2orf69 in more than 4 cancer types. Because this analysis shows association rather than direction, both C2orf69-to-partner and partner-to-C2orf69 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C2orf69 versus ORC3 in LSCC, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf69→partner) and Y-score (partner→C2orf69) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ORC3 →	+0.367	+0.623	<.001	<.001	3	5
LSCC	SPAST →	+0.336	+0.533	.001	<.001	3	5
LUAD	NCAPD2 →	+0.471	+0.304	<.001	.002	3	4
LUAD	NCAPG →	+0.493	+0.324	<.001	<.001	3	4
GBM	NFKB1 →	-0.322	-0.586	<.001	<.001	3	4
LSCC	ORC5 →	+0.350	+0.557	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,084 associations by consensus.

C2orf69 vs ORC3 — LSCC

Explore this scatter interactively →