C2orf69

Across TCGA patient cohorts, C2orf69 mutation is significantly associated with the RNA expression of many other genes, with 398 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C2orf69-associated genes across cancer lineages are RNU4-79P, MTATP6P29, and SQSTM1P1. Each is linked with C2orf69 in more than 1 cancer types. Because this analysis shows association rather than direction, both C2orf69-to-partner and partner-to-C2orf69 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-79P grouped by C2orf69-low versus C2orf69-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf69→partner) and Y-score (partner→C2orf69) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU4-79P →	+0.363	+7.640	<.001	.009	3	2
UCEC	MTATP6P29 →	+0.260	+2.674	<.001	.006	3	2
UCEC	SQSTM1P1 →	+0.057	+2.572	.002	.007	3	1
UCEC	DOC2B →	-1.329	-3.807	<.001	<.001	3	1
UCEC	MAP3K4-AS1 →	+0.880	+3.467	<.001	.002	3	1
UCEC	TAF9 →	+0.537	+2.700	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 398 associations by consensus.

RNU4-79P by C2orf69 expression — BLCA

Explore this box plot interactively →