C2orf69

Across TCGA cell cohorts, C2orf69 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,550 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C2orf69-associated GO terms across cancer lineages are Centrosome cycle, Microtubule organizing center organization, and Positive regulation of cell cycle. Each is linked with C2orf69 in more than 16 cancer types. Because this analysis shows association rather than direction, both C2orf69-to-partner and partner-to-C2orf69 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centrosome cycle grouped by C2orf69-low versus C2orf69-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf69→partner) and Y-score (partner→C2orf69) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Centrosome cycle →	+0.085	+0.835	<.001	<.001	3	17
PANCREAS	Microtubule organizing center organization →	+0.081	+0.835	<.001	<.001	3	16
BREAST	Positive regulation of cell cycle →	+0.074	+0.687	<.001	<.001	3	16
LUNG_SCLC	Regulation of centrosome duplication →	+0.083	+0.683	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Centrosome duplication →	+0.099	+1.003	<.001	<.001	3	15
BREAST	Regulation of metaphase/anaphase transition of cell cycle →	+0.103	+0.663	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,550 associations by consensus.

Centrosome cycle by C2orf69 expression — PANCREAS

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