C2orf68

Across TCGA patient cohorts, C2orf68 mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C2orf68-associated genes across cancer lineages are RNU6-200P, RNU6-1292P, and RNY4P29. Each is linked with C2orf68 in more than 1 cancer types. Because this analysis shows association rather than direction, both C2orf68-to-partner and partner-to-C2orf68 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-200P grouped by C2orf68-low versus C2orf68-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf68→partner) and Y-score (partner→C2orf68) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-200P →	+0.211	+4.923	<.001	.002	3	2
UCEC	RNU6-1292P →	+0.595	+5.038	<.001	<.001	3	2
UCEC	RNY4P29 →	+0.232	+5.414	<.001	.001	3	2
LUSC	BNIP3P20 →	+0.127	+5.151	.004	.007	3	2
COAD	MTND3P1 →	+0.319	+4.602	<.001	.008	3	1
COAD	EEF1A1P39 →	+0.361	+4.324	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

RNU6-200P by C2orf68 expression — UCEC

Explore this box plot interactively →