C2orf42

Across TCGA patient cohorts, C2orf42 protein abundance is significantly associated with the RNA expression of many other genes, with 7,941 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible C2orf42-associated genes across cancer lineages are VWA5A, CXCL8, and FCAR. Each is linked with C2orf42 in more than 2 cancer types. Because this analysis shows association rather than direction, both C2orf42-to-partner and partner-to-C2orf42 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C2orf42 versus VWA5A in HNSC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf42→partner) and Y-score (partner→C2orf42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VWA5A →	-0.710	-0.810	.007	<.001	3	3
LUAD	CXCL8 →	+2.109	+0.699	<.001	<.001	3	3
PDAC	FCAR →	+0.681	+1.278	.002	.005	3	3
HNSC	SPATA9 →	-0.343	-0.775	<.001	<.001	3	3
PDAC	DLC1 →	-0.609	-1.615	.003	.006	3	3
LUAD	MEST →	+0.550	+0.456	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,941 associations by consensus.

C2orf42 vs VWA5A — HNSC

Explore this scatter interactively →