C2orf42

Across TCGA cell cohorts, C2orf42 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C2orf42-associated genes across cancer lineages are OR10R2, BHLHE23, and NGF. Each is linked with C2orf42 in more than 1 cancer types. Because this analysis shows association rather than direction, both C2orf42-to-partner and partner-to-C2orf42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10R2 grouped by C2orf42-low versus C2orf42-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf42→partner) and Y-score (partner→C2orf42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR10R2 →	+1.994	+5.288	<.001	<.001	3	2
BLOOD_Leukemia	BHLHE23 →	+1.579	+3.691	<.001	.005	3	1
BLOOD_Leukemia	NGF →	+0.377	+3.594	<.001	.007	3	1
BLOOD_Leukemia	NPFFR1 →	+0.014	+4.359	<.001	<.001	3	1
BLOOD_Leukemia	CD1B →	+6.255	+3.619	<.001	.007	3	1
BLOOD_Leukemia	DIRAS2 →	+0.102	+3.551	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

OR10R2 by C2orf42 expression — BLOOD_Leukemia

Explore this box plot interactively →