C2CD5

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C2CD5 protein abundance is significantly associated with the RNA expression of many other genes, with 18,594 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C2CD5-associated genes across cancer lineages are FN1, DUSP16, and TGFBI. Each is linked with C2CD5 in more than 5 cancer types. Because this analysis shows association rather than direction, both C2CD5-to-partner and partner-to-C2CD5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C2CD5 versus FN1 in GBM, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD5→partner) and Y-score (partner→C2CD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMFN1 →-1.147-0.208<.001<.00136
BRCADUSP16 →+0.691+0.261<.001.00135
HNSCTGFBI →-1.197-0.182<.001<.00135
HNSCETNK1 →+0.478+0.284<.001<.00135
GBMRAVER2 →+0.599+0.249<.001<.00135
GBMPDLIM7 →-0.612-0.180<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,594 associations by consensus.

C2CD5 vs FN1 — GBM

Per-sample scatter of C2CD5 vs FN1 in GBM (Pearson r = -0.36).

Explore this scatter interactively →

Exploration