C2CD5

Across TCGA cell cohorts, C2CD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,894 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C2CD5-associated GO terms across cancer lineages are Constitutive heterochromatin formation, Heterochromatin formation, and Epigenetic regulation of gene expression. Each is linked with C2CD5 in more than 18 cancer types. Because this analysis shows association rather than direction, both C2CD5-to-partner and partner-to-C2CD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Constitutive heterochromatin formation grouped by C2CD5-low versus C2CD5-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD5→partner) and Y-score (partner→C2CD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Constitutive heterochromatin formation →	+0.093	+0.917	<.001	<.001	3	19
SOFT_TISSUE	Heterochromatin formation →	+0.062	+0.865	<.001	<.001	3	17
BONE	Epigenetic regulation of gene expression →	+0.068	+0.632	<.001	.002	3	17
UPPER_AERODIGESTIVE_TRACT	Regulation of microtubule-based process →	+0.070	+1.619	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Negative regulation of gene expression, epigenetic →	+0.067	+1.469	<.001	<.001	3	16
BLOOD_Lymphoma	Heterochromatin organization →	+0.056	+0.983	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,894 associations by consensus.

Constitutive heterochromatin formation by C2CD5 expression — SOFT_TISSUE

Explore this box plot interactively →