C2CD5

Across TCGA cell cohorts, C2CD5 mutation is significantly associated with the RNA expression of many other genes, with 137 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C2CD5-associated genes across cancer lineages are LRFN2, PATE1, and SUPT20HL1. Each is linked with C2CD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both C2CD5-to-partner and partner-to-C2CD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LRFN2 grouped by C2CD5-low versus C2CD5-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD5→partner) and Y-score (partner→C2CD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	LRFN2 →	+0.018	+4.754	.006	.001	3	2
OVARY	PATE1 →	+0.039	+3.974	<.001	.002	3	2
OVARY	SUPT20HL1 →	+0.061	+3.807	.001	.009	3	2
SKIN	GUCA2A →	+0.102	+4.273	<.001	.006	3	2
LUNG_NSCLC_LUSC	VSIG4 →	+0.036	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	HTR5A →	+0.006	+4.643	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 137 associations by consensus.

LRFN2 by C2CD5 expression — OVARY

Explore this box plot interactively →