C2CD4C

Across TCGA cell cohorts, C2CD4C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,928 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C2CD4C-associated GO terms across cancer lineages are Regulation of protein localization to centrosome, Proton motive force-driven ATP synthesis, and Proton motive force-driven mitochondrial ATP synthesis. Each is linked with C2CD4C in more than 10 cancer types. Because this analysis shows association rather than direction, both C2CD4C-to-partner and partner-to-C2CD4C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to centrosome grouped by C2CD4C-low versus C2CD4C-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD4C→partner) and Y-score (partner→C2CD4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of protein localization to centrosome →	+0.136	+1.986	<.001	<.001	3	10
BONE	Proton motive force-driven ATP synthesis →	+0.124	+1.897	<.001	<.001	3	10
BONE	Proton motive force-driven mitochondrial ATP synthesis →	+0.118	+1.873	<.001	<.001	3	10
BONE	Nucleoside triphosphate biosynthetic process →	+0.141	+2.033	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Negative regulation of glucagon secretion →	+1.464	+1.160	<.001	.003	2	11
OESOPHAGUS	U2-type prespliceosome assembly →	+0.131	+1.616	.003	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,928 associations by consensus.

Regulation of protein localization to centrosome by C2CD4C expression — LUNG_SCLC

Explore this box plot interactively →