Across TCGA pan-cancer cohorts, C2CD4B Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated C2CD4B data layer compared with 22 for mass-spec protein and 1 for mass-spec protein.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher C2CD4B Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C2CD4B expression acts as an unfavorable survival marker.
LIHC are the cancer types where C2CD4B Mutation most reproducibly stratifies survival.