Across TCGA patient cohorts, C2CD4B protein abundance is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible C2CD4B-associated genes across cancer lineages are TMPRSS6, RNU6-144P, and ACTN4P2. Each is linked with C2CD4B in more than 1 cancer types. Because this analysis shows association rather than direction, both C2CD4B-to-partner and partner-to-C2CD4B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD4B→partner) and Y-score (partner→C2CD4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TMPRSS6 →	-0.955	-1.390	.007	.006	3	1
PDAC	RNU6-144P →	+1.027	+1.222	.009	<.001	3	1
PDAC	ACTN4P2 →	+0.051	+1.017	.004	.001	3	1
PDAC	MIR942 →	-1.473	-1.130	<.001	.008	3	1
PDAC	PAPPA-AS2 →	+0.734	+1.101	.003	.006	3	1
PDAC	SPATS1 →	+0.070	+1.044	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

C2CD4B survival (RNA) · tumor vs normal (RNA) · all C2CD4B data types