Across TCGA cell cohorts, C2CD4B mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C2CD4B-associated genes across cancer lineages are MYH8, COX6A2, and DEFA4. Each is linked with C2CD4B in more than 1 cancer types. Because this analysis shows association rather than direction, both C2CD4B-to-partner and partner-to-C2CD4B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD4B→partner) and Y-score (partner→C2CD4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MYH8 →	+0.092	+3.920	<.001	.005	3	1
LARGE_INTESTINE	COX6A2 →	+0.082	+4.437	<.001	.004	3	1
LARGE_INTESTINE	DEFA4 →	+0.032	+4.437	<.001	.004	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.012	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

C2CD4B survival (RNA) · tumor vs normal (RNA) · all C2CD4B data types