C2CD4B

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C2CD4B mutation is significantly associated with the mutation status of many other genes, with 419 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C2CD4B-associated genes across cancer lineages are PPAN-P2RY11, MAST2, and TAFA5. Each is linked with C2CD4B in more than 1 cancer types. Because this analysis shows association rather than direction, both C2CD4B-to-partner and partner-to-C2CD4B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD4B→partner) and Y-score (partner→C2CD4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaPPAN-P2RY11 →+5.014+5.584.003.00312
LARGE_INTESTINEMAST2 →+2.159+3.807.007.00712
LARGE_INTESTINETAFA5 →+3.007+3.584.008.00812
BLOOD_LymphomaDIAPH1 →+4.014+4.969.008.00812
BLOOD_LymphomaSETDB2 →+6.014+6.014.001.00112
BLOOD_LymphomaPRR14 →+5.014+5.584.003.00312
Each partner links to its Q-omics profile. Showing the 6 strongest of 419 associations by consensus.

Exploration