Across TCGA pan-cancer cohorts, C2CD4A Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated C2CD4A data layer compared with 24 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher C2CD4A Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated C2CD4A expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC are the cancer types where C2CD4A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	1.000	0.445	.040	2	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: C2CD4A tumor-vs-normal RNA expression · all C2CD4A data types