Across TCGA cell cohorts, C2CD4A mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C2CD4A-associated genes across cancer lineages are GAGE12J and FCN2. Each is linked with C2CD4A in more than 1 cancer types. Because this analysis shows association rather than direction, both C2CD4A-to-partner and partner-to-C2CD4A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD4A→partner) and Y-score (partner→C2CD4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	GAGE12J →	+0.266	+4.643	<.001	.008	3	1
LARGE_INTESTINE	FCN2 →	+0.024	+5.415	.007	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

C2CD4A survival (RNA) · tumor vs normal (RNA) · all C2CD4A data types