C2CD3

Across TCGA patient cohorts, C2CD3 protein abundance is significantly associated with the protein abundance of many other proteins, with 7,017 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C2CD3-associated proteins across cancer lineages are C2CD3_S2114, ACTR3, and ARID5B_S264. Each is linked with C2CD3 in more than 2 cancer types. Because this analysis shows association rather than direction, both C2CD3-to-partner and partner-to-C2CD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C2CD3 versus C2CD3_S2114 in LSCC, with a Pearson correlation of 0.71.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD3→partner) and Y-score (partner→C2CD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	C2CD3_S2114 →	+0.425	+0.208	<.001	<.001	3	3
PDAC	ACTR3 →	-0.341	-0.901	<.001	.006	3	2
BRCA	ARID5B_S264 →	-0.525	-0.311	<.001	<.001	3	2
LSCC	ALPK3 →	+1.230	+0.498	.005	.002	3	2
UCEC	AKAP6_S1335 →	+0.846	+0.298	<.001	.001	3	2
GBM	ARVCF_S203 →	+0.875	+0.348	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,017 associations by consensus.

C2CD3 vs C2CD3_S2114 — LSCC

Explore this scatter interactively →