C2CD3

Across TCGA cell cohorts, C2CD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,899 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C2CD3-associated GO terms across cancer lineages are Centriole elongation, Centrosome cycle, and Protein localization to cytoskeleton. Each is linked with C2CD3 in more than 18 cancer types. Because this analysis shows association rather than direction, both C2CD3-to-partner and partner-to-C2CD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centriole elongation grouped by C2CD3-low versus C2CD3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD3→partner) and Y-score (partner→C2CD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Centriole elongation →	+0.165	+1.328	<.001	<.001	3	19
SOFT_TISSUE	Centrosome cycle →	+0.089	+1.118	<.001	<.001	3	15
LARGE_INTESTINE	Protein localization to cytoskeleton →	+0.069	+0.982	<.001	<.001	3	15
PANCREAS	DNA strand elongation →	+0.172	+1.134	<.001	<.001	3	14
SOFT_TISSUE	Microtubule organizing center organization →	+0.079	+0.971	<.001	.001	3	14
SOFT_TISSUE	Chromosome condensation →	+0.169	+1.048	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,899 associations by consensus.

Centriole elongation by C2CD3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →