C2CD3

Across TCGA cell cohorts, C2CD3 mutation is significantly associated with the RNA expression of many other genes, with 1,363 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C2CD3-associated genes across cancer lineages are CD300H, PROP1, and EIF3D. Each is linked with C2CD3 in more than 3 cancer types. Because this analysis shows association rather than direction, both C2CD3-to-partner and partner-to-C2CD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300H grouped by C2CD3-low versus C2CD3-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD3→partner) and Y-score (partner→C2CD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CD300H →	+0.097	+3.169	<.001	.005	3	4
OESOPHAGUS	PROP1 →	+0.030	+4.906	<.001	.006	3	3
LARGE_INTESTINE	EIF3D →	+0.347	+2.364	.006	<.001	3	3
LUNG_SCLC	BNC1 →	+0.370	+3.343	.008	.005	3	2
LUNG_SCLC	C18orf63 →	+0.006	+3.169	<.001	.005	3	2
LARGE_INTESTINE	TNRC6B →	+0.635	+2.764	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,363 associations by consensus.

CD300H by C2CD3 expression — LUNG_SCLC

Explore this box plot interactively →