C2CD2L

Across TCGA patient cohorts, C2CD2L mutation is significantly associated with the RNA expression of many other genes, with 1,441 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C2CD2L-associated genes across cancer lineages are TBC1D3C, CPSF4, and MON1A. Each is linked with C2CD2L in more than 1 cancer types. Because this analysis shows association rather than direction, both C2CD2L-to-partner and partner-to-C2CD2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBC1D3C grouped by C2CD2L-low versus C2CD2L-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD2L→partner) and Y-score (partner→C2CD2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	TBC1D3C →	+0.015	+5.268	.001	.006	3	2
UCEC	CPSF4 →	+0.392	+2.609	.007	.006	3	2
UCEC	MON1A →	+0.454	+3.470	<.001	.002	3	2
UCEC	COX10 →	+0.371	+2.321	.009	.006	3	2
LIHC	MIR4285 →	+0.369	+5.186	.002	.007	3	2
LUSC	UBTFL3 →	+0.030	+4.321	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,441 associations by consensus.

TBC1D3C by C2CD2L expression — LIHC

Explore this box plot interactively →