C2CD2L

Across TCGA cell cohorts, C2CD2L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,292 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible C2CD2L-associated GO terms across cancer lineages are Regulation of autophagosome maturation, Pre-mRNA catabolic process, and Post-Golgi vesicle-mediated transport. Each is linked with C2CD2L in more than 10 cancer types. Because this analysis shows association rather than direction, both C2CD2L-to-partner and partner-to-C2CD2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of autophagosome maturation grouped by C2CD2L-low versus C2CD2L-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD2L→partner) and Y-score (partner→C2CD2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of autophagosome maturation →	+0.106	+1.086	.001	.002	3	11
BONE	Pre-mRNA catabolic process →	+0.235	+0.931	.001	.002	3	11
UPPER_AERODIGESTIVE_TRACT	Post-Golgi vesicle-mediated transport →	+0.078	+0.728	<.001	.002	3	11
BONE	Transcription pausing by RNA polymerase II →	+0.145	+0.803	.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of TORC2 signaling →	+0.115	+1.006	<.001	.002	2	11
BLOOD_Leukemia	Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II →	-0.193	-0.718	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,292 associations by consensus.

Regulation of autophagosome maturation by C2CD2L expression — URINARY_TRACT

Explore this box plot interactively →