C2CD2L

Across TCGA cell cohorts, C2CD2L mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C2CD2L-associated genes across cancer lineages are OPRPN, OR2A2, and CDH20. Each is linked with C2CD2L in more than 1 cancer types. Because this analysis shows association rather than direction, both C2CD2L-to-partner and partner-to-C2CD2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPRPN grouped by C2CD2L-low versus C2CD2L-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD2L→partner) and Y-score (partner→C2CD2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OPRPN →	+0.045	+4.087	<.001	.009	3	1
URINARY_TRACT	OR2A2 →	+0.035	+4.087	<.001	.009	3	1
LARGE_INTESTINE	CDH20 →	+0.123	+3.029	<.001	.003	3	1
LARGE_INTESTINE	RASGEF1C →	+0.275	+3.555	<.001	.003	3	1
LARGE_INTESTINE	ACER1 →	+0.074	+3.408	.003	<.001	3	1
LARGE_INTESTINE	KCND3 →	+0.385	+3.548	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

OPRPN by C2CD2L expression — URINARY_TRACT

Explore this box plot interactively →