C2CD2

Across TCGA patient cohorts, C2CD2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,198 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C2CD2-associated genes across cancer lineages are ADRB2, ASAH1, and C4BPA. Each is linked with C2CD2 in more than 3 cancer types. Because this analysis shows association rather than direction, both C2CD2-to-partner and partner-to-C2CD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C2CD2 versus ADRB2 in HNSC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD2→partner) and Y-score (partner→C2CD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ADRB2 →	+1.306	+0.308	<.001	.008	3	4
LSCC	ASAH1 →	+0.531	+0.350	<.001	<.001	3	3
LSCC	C4BPA →	+1.823	+0.294	.001	.001	3	3
GBM	FANCD2 →	-0.631	-0.280	<.001	<.001	3	3
LUAD	C16orf89 →	+1.331	+0.278	<.001	<.001	3	3
LSCC	TSPAN18 →	-1.073	-0.230	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,198 associations by consensus.

C2CD2 vs ADRB2 — HNSC

Explore this scatter interactively →