C2CD2

Across TCGA cell cohorts, C2CD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,243 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C2CD2-associated GO terms across cancer lineages are Retrograde transport, endosome to Golgi, Endosomal transport, and Establishment of protein localization to plasma membrane. Each is linked with C2CD2 in more than 10 cancer types. Because this analysis shows association rather than direction, both C2CD2-to-partner and partner-to-C2CD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Retrograde transport, endosome to Golgi grouped by C2CD2-low versus C2CD2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD2→partner) and Y-score (partner→C2CD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Retrograde transport, endosome to Golgi →	+0.092	+1.326	<.001	<.001	3	11
BONE	Endosomal transport →	+0.079	+2.530	<.001	<.001	3	11
BONE	Establishment of protein localization to plasma membrane →	+0.099	+1.792	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Golgi to plasma membrane protein transport →	+0.161	+1.461	<.001	.001	3	10
URINARY_TRACT	Schwann cell differentiation →	+0.154	+1.027	<.001	.004	3	10
CNS	Phosphatidylinositol biosynthetic process →	+0.044	+0.949	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,243 associations by consensus.

Retrograde transport, endosome to Golgi by C2CD2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →