Across TCGA patient cohorts, C22orf42 mutation is significantly associated with the RNA expression of many other genes, with 330 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible C22orf42-associated genes across cancer lineages are MIR8075, RNA5SP531, and MIR4752. Each is linked with C22orf42 in more than 1 cancer types. Because this analysis shows association rather than direction, both C22orf42-to-partner and partner-to-C22orf42 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf42→partner) and Y-score (partner→C22orf42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR8075 →	+1.007	+3.086	.001	.003	3	2
SKCM	RNA5SP531 →	+0.078	+4.321	<.001	.003	3	2
LUAD	MIR4752 →	+0.338	+5.584	<.001	.002	3	2
SKCM	ACTN1-AS1 →	+0.274	+2.925	<.001	.001	3	2
UCEC	RNU6-541P →	+0.552	+3.960	<.001	<.001	3	2
SKCM	FAM50A →	+0.449	+4.019	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 330 associations by consensus.

Exploration

C22orf42 survival (RNA) · tumor vs normal (RNA) · all C22orf42 data types