Across TCGA patient cohorts, C22orf42 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible C22orf42-associated genes across cancer lineages are MEP, CD8+ T-cells, and CMP. Each is linked with C22orf42 in more than 1 cancer types. Because this analysis shows association rather than direction, both C22orf42-to-partner and partner-to-C22orf42 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf42→partner) and Y-score (partner→C22orf42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MEP →	+0.028	+1.732	.015	.026	3	2
LUAD	CD8+ T-cells →	+0.044	+3.899	.005	.015	3	1
LUSC	CMP →	+0.049	+4.052	<.001	.003	3	1
LUSC	Eosinophils →	+0.035	+2.588	.003	.036	3	1
UCEC	Myocytes →	+0.054	+3.042	.003	.018	1	2

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

C22orf42 survival (RNA) · tumor vs normal (RNA) · all C22orf42 data types