Across TCGA cell cohorts, C22orf42 RNA expression is significantly associated with the go_rna of many other GO terms, with 596 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible C22orf42-associated GO terms across cancer lineages are Response to caloric restriction, Regulation of hematopoietic stem cell proliferation, and Leukocyte activation involved in immune response. Each is linked with C22orf42 in more than 3 cancer types. Because this analysis shows association rather than direction, both C22orf42-to-partner and partner-to-C22orf42 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf42→partner) and Y-score (partner→C22orf42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Response to caloric restriction →	+0.120	+0.033	<.001	.002	3	4
CNS	Regulation of hematopoietic stem cell proliferation →	+0.065	+0.033	.008	.001	3	3
CNS	Leukocyte activation involved in immune response →	+0.027	+0.042	.009	.003	3	3
SKIN	Replacement ossification →	-0.121	-0.090	.001	<.001	3	3
SKIN	Pyrimidine nucleoside catabolic process →	+0.164	+0.099	.006	<.001	3	3
SKIN	Protein K6-linked ubiquitination →	+0.042	+0.077	.005	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 596 associations by consensus.

Exploration

C22orf42 survival (RNA) · tumor vs normal (RNA) · all C22orf42 data types