Across TCGA patient cohorts, C22orf34 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,596 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C22orf34-associated proteins across cancer lineages are HCLS1, ANKRD44, and RENBP. Each is linked with C22orf34 in more than 8 cancer types. Because this analysis shows association rather than direction, both C22orf34-to-partner and partner-to-C22orf34 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf34→partner) and Y-score (partner→C22orf34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HCLS1 →	+0.685	+0.534	<.001	<.001	3	9
OV	ANKRD44 →	+0.505	+0.235	<.001	<.001	3	9
OV	RENBP →	+0.463	+0.284	<.001	<.001	3	8
GBM	LCP1 →	+0.740	+0.525	<.001	<.001	3	8
UCEC	ADPRH →	+0.499	+0.706	<.001	.004	3	8
GBM	DOCK8 →	+0.520	+0.543	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,596 associations by consensus.

Exploration

C22orf34 survival (RNA) · tumor vs normal (RNA) · all C22orf34 data types