C22orf15

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C22orf15 mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C22orf15-associated genes across cancer lineages are PDK1_pS241. Each is linked with C22orf15 in more than 1 cancer types. Because this analysis shows association rather than direction, both C22orf15-to-partner and partner-to-C22orf15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDK1_pS241 grouped by C22orf15-low versus C22orf15-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf15→partner) and Y-score (partner→C22orf15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPDK1_pS241 →+0.320+2.820.002.03631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

PDK1_pS241 by C22orf15 expression — UCEC

Box plot of PDK1_pS241 in C22orf15-low vs C22orf15-high samples in UCEC.

Explore this box plot interactively →

Exploration