C22orf15

Across TCGA cell cohorts, C22orf15 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,870 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C22orf15-associated GO terms across cancer lineages are mRNA alternative polyadenylation, Positive regulation of transmembrane transport, and Negative regulation of gene expression, epigenetic. Each is linked with C22orf15 in more than 9 cancer types. Because this analysis shows association rather than direction, both C22orf15-to-partner and partner-to-C22orf15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA alternative polyadenylation grouped by C22orf15-low versus C22orf15-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf15→partner) and Y-score (partner→C22orf15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	mRNA alternative polyadenylation →	+0.072	+0.105	<.001	.008	3	10
BONE	Positive regulation of transmembrane transport →	-0.077	-2.120	<.001	<.001	3	10
OVARY	Negative regulation of gene expression, epigenetic →	+0.052	+0.141	.007	.009	2	10
PANCREAS	Positive regulation of monoatomic ion transport →	-0.115	-0.191	<.001	.006	3	9
UPPER_AERODIGESTIVE_TRACT	Epigenetic regulation of gene expression →	+0.067	+0.246	<.001	<.001	3	9
BONE	Nucleic acid catabolic process →	+0.055	+2.202	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,870 associations by consensus.

mRNA alternative polyadenylation by C22orf15 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →