Across TCGA patient cohorts, C21orf62 mutation is significantly associated with the RNA expression of many other genes, with 3,408 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C21orf62-associated genes across cancer lineages are UBE2Q2P10, RN7SKP113, and RNU6-980P. Each is linked with C21orf62 in more than 1 cancer types. Because this analysis shows association rather than direction, both C21orf62-to-partner and partner-to-C21orf62 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C21orf62→partner) and Y-score (partner→C21orf62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	UBE2Q2P10 →	+0.085	+5.010	<.001	.009	3	2
BLCA	RN7SKP113 →	+0.143	+7.640	<.001	.009	3	2
SKCM	RNU6-980P →	+0.524	+5.436	<.001	.005	3	2
SKCM	OR2T3 →	+0.083	+5.097	<.001	.008	3	2
BLCA	OR4A7P →	+0.049	+7.640	<.001	.009	3	2
UCEC	RNA5SP418 →	+0.604	+1.956	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,408 associations by consensus.

Exploration

C21orf62 survival (RNA) · tumor vs normal (RNA) · all C21orf62 data types