Across TCGA cell cohorts, C21orf62 mutation is significantly associated with the mutation status of many other genes, with 451 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C21orf62-associated genes across cancer lineages are AQP1, MAVS, and DMPK. Each is linked with C21orf62 in more than 1 cancer types. Because this analysis shows association rather than direction, both C21orf62-to-partner and partner-to-C21orf62 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C21orf62→partner) and Y-score (partner→C21orf62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AQP1 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	MAVS →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	DMPK →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	UXS1 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	NT5C3A →	+5.523	+5.523	.003	.003	1	2
LARGE_INTESTINE	LBX1 →	+4.523	+5.087	.006	.006	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 451 associations by consensus.

Exploration

C21orf62 survival (RNA) · tumor vs normal (RNA) · all C21orf62 data types