C21orf58

Across TCGA cell cohorts, C21orf58 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,464 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C21orf58-associated GO terms across cancer lineages are Microtubule organizing center organization, Double-strand break repair, and Chromosome condensation. Each is linked with C21orf58 in more than 18 cancer types. Because this analysis shows association rather than direction, both C21orf58-to-partner and partner-to-C21orf58 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule organizing center organization grouped by C21orf58-low versus C21orf58-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C21orf58→partner) and Y-score (partner→C21orf58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Microtubule organizing center organization →	+0.101	+1.782	<.001	<.001	3	19
BONE	Double-strand break repair →	+0.097	+1.825	.001	<.001	3	19
BONE	Chromosome condensation →	+0.229	+2.120	<.001	<.001	3	18
BONE	DNA recombination →	+0.099	+1.515	<.001	<.001	3	18
BONE	Mitotic nuclear division →	+0.109	+1.513	.003	<.001	3	17
URINARY_TRACT	Regulation of cell cycle G2/M phase transition →	+0.078	+1.380	<.001	.002	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,464 associations by consensus.

Microtubule organizing center organization by C21orf58 expression — BONE

Explore this box plot interactively →