C20orf194

Across TCGA pan-cancer cohorts, C20orf194 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated C20orf194 data layer compared with 22 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher C20orf194 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated C20orf194 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LSCC show a favorable association.

LUAD, PDAC, and UCEC are the cancer types where C20orf194 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	III,IV	0.156	0.840	<.001	62	view →
PDAC	DFS	Median	III,IV	0.711	0.263	.008	11	view →
UCEC	OS	Quartile	All	0.780	1.000	.013	10	view →
GBM	DFS	Tertile	All	0.220	0.433	.027	6	view →
LSCC	DFS	Median	III,IV	0.900	0.433	.012	4	view →
CCRCC	OS	Median	IV	0.789	0.199	.025	4	view →
HNSC	OS	Quartile	III,IV	0.654	0.979	.016	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

C20orf194–LUAD (OS)

Open the LUAD breakdown →