C20orf194

Across TCGA patient cohorts, C20orf194 mutation is significantly associated with the RNA expression of many other genes, with 2,328 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C20orf194-associated genes across cancer lineages are MIR6500, RNU4-4P, and RNU1-74P. Each is linked with C20orf194 in more than 4 cancer types. Because this analysis shows association rather than direction, both C20orf194-to-partner and partner-to-C20orf194 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6500 grouped by C20orf194-low versus C20orf194-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C20orf194→partner) and Y-score (partner→C20orf194) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR6500 →	+0.243	+3.498	.008	.006	3	5
HNSC	RNU4-4P →	+0.314	+3.623	.001	.001	3	3
HNSC	RNU1-74P →	+0.231	+3.767	.002	.003	3	3
CESC	SPATA8-AS1 →	+0.230	+4.384	<.001	.008	3	3
READ	MIR4774 →	+0.841	+6.257	<.001	.001	3	3
SKCM	MED18 →	+0.413	+3.347	.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,328 associations by consensus.

MIR6500 by C20orf194 expression — HNSC

Explore this box plot interactively →