C20orf194

Across TCGA patient cohorts, C20orf194 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C20orf194-associated genes across cancer lineages are Notch1, PRAS40_pT246, and ATM. Each is linked with C20orf194 in more than 1 cancer types. Because this analysis shows association rather than direction, both C20orf194-to-partner and partner-to-C20orf194 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by C20orf194-low versus C20orf194-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C20orf194→partner) and Y-score (partner→C20orf194) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.101	+1.498	.022	.032	3	2
UCEC	PRAS40_pT246 →	+0.116	+1.150	.031	.028	3	2
UCEC	ATM →	-0.385	-1.794	.006	.024	3	2
UCEC	Caspase-7-cleavedD198 →	+0.415	+1.807	.026	.024	3	2
UCEC	Cyclin-B1 →	+0.416	+2.459	.018	.018	3	2
UCEC	Fibronectin →	-0.205	-1.755	.048	.013	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Notch1 by C20orf194 expression — UCEC

Explore this box plot interactively →