C1orf94

Across TCGA patient cohorts, C1orf94 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1orf94-associated genes across cancer lineages are ATM, Cyclin-B1, and Caspase-7-cleavedD198. Each is linked with C1orf94 in more than 2 cancer types. Because this analysis shows association rather than direction, both C1orf94-to-partner and partner-to-C1orf94 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by C1orf94-low versus C1orf94-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf94→partner) and Y-score (partner→C1orf94) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.581	-1.893	<.001	<.001	3	3
UCEC	Cyclin-B1 →	+0.513	+2.222	.003	.010	3	3
COAD	Caspase-7-cleavedD198 →	+1.196	+3.178	.002	.010	3	2
UCEC	mTOR_pS2448 →	-0.124	-1.717	.007	.006	3	2
UCEC	PCNA →	+0.208	+1.893	.001	<.001	3	2
UCEC	STAT3_pY705 →	-0.336	-1.415	<.001	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

ATM by C1orf94 expression — UCEC

Explore this box plot interactively →