C1orf87

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C1orf87 mutation is significantly associated with the RNA expression of many other genes, with 1,709 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1orf87-associated genes across cancer lineages are CENPU, LINC01639, and OR4F28P. Each is linked with C1orf87 in more than 2 cancer types. Because this analysis shows association rather than direction, both C1orf87-to-partner and partner-to-C1orf87 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENPU grouped by C1orf87-low versus C1orf87-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf87→partner) and Y-score (partner→C1orf87) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCENPU →+0.555+2.158.004.00933
BLCALINC01639 →+0.840+3.788<.001.00933
PRADOR4F28P →+0.086+5.109<.001.00833
UCECGOT1 →+0.379+2.743.002.00233
HNSCCTAG1B →+0.040+4.526<.001.00733
SKCMNME1-NME2 →+0.427+2.719.008.00333
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,709 associations by consensus.

CENPU by C1orf87 expression — UCEC

Box plot of CENPU in C1orf87-low vs C1orf87-high samples in UCEC.

Explore this box plot interactively →

Exploration