C1orf87

Across TCGA patient cohorts, C1orf87 mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1orf87-associated genes across cancer lineages are Rab25, GAPDH, and HER3_pY1289. Each is linked with C1orf87 in more than 2 cancer types. Because this analysis shows association rather than direction, both C1orf87-to-partner and partner-to-C1orf87 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rab25 grouped by C1orf87-low versus C1orf87-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf87→partner) and Y-score (partner→C1orf87) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Rab25 →	-0.256	-3.442	.006	.004	3	3
UCEC	GAPDH →	+0.380	+2.459	.041	.018	3	3
STAD	HER3_pY1289 →	+0.114	+2.828	.021	.035	3	2
UCEC	JNK2 →	+0.238	+2.026	<.001	.016	3	2
SKCM	Snail →	-0.153	-2.209	.017	.009	3	2
UCEC	p27_pT157 →	-0.063	-2.571	.001	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Rab25 by C1orf87 expression — SKCM

Explore this box plot interactively →