C1orf87

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C1orf87 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C1orf87-associated genes across cancer lineages are TAAR6, KCNK16, and ADAM2. Each is linked with C1orf87 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf87-to-partner and partner-to-C1orf87 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAAR6 grouped by C1orf87-low versus C1orf87-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf87→partner) and Y-score (partner→C1orf87) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaTAAR6 →+0.043+4.807<.001.00632
BLOOD_MyelomaKCNK16 →+0.030+4.807<.001.00631
BLOOD_LeukemiaADAM2 →+0.144+4.539<.001.00731
BLOOD_LeukemiaC1QL2 →+0.011+5.507<.001<.00131
BLOOD_LeukemiaOR10Q1 →+0.016+4.969<.001.00331
BLOOD_LeukemiaGFRAL →+0.025+5.569<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

TAAR6 by C1orf87 expression — BLOOD_Myeloma

Box plot of TAAR6 in C1orf87-low vs C1orf87-high samples in BLOOD_Myeloma.

Explore this box plot interactively →

Exploration