C1orf56

Across TCGA patient cohorts, C1orf56 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,105 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C1orf56-associated proteins across cancer lineages are RPRD2, NAXE, and RPRD2_T732. Each is linked with C1orf56 in more than 6 cancer types. Because this analysis shows association rather than direction, both C1orf56-to-partner and partner-to-C1orf56 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf56 versus RPRD2 in LSCC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf56→partner) and Y-score (partner→C1orf56) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RPRD2 →	+0.287	+0.577	<.001	<.001	3	7
UCEC	NAXE →	+0.345	+0.536	<.001	<.001	3	7
HNSC	RPRD2_T732 →	+0.727	+0.534	<.001	.002	3	6
GBM	STK10 →	-0.385	-0.298	<.001	.001	3	6
LSCC	STRBP →	+0.629	+0.622	<.001	<.001	3	6
UCEC	BROX →	+0.427	+0.415	<.001	.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,105 associations by consensus.

C1orf56 vs RPRD2 — LSCC

Explore this scatter interactively →