C1orf56

Across TCGA patient cohorts, C1orf56 protein abundance is significantly associated with the RNA expression of many other genes, with 2,212 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible C1orf56-associated genes across cancer lineages are SEMA3G, PCDH12, and FNDC4. Each is linked with C1orf56 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf56-to-partner and partner-to-C1orf56 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf56 versus SEMA3G in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf56→partner) and Y-score (partner→C1orf56) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEMA3G →	+1.086	+0.571	.002	.009	3	2
LSCC	PCDH12 →	+0.932	+0.524	.001	.003	3	2
LSCC	FNDC4 →	+1.355	+0.491	<.001	<.001	3	2
LSCC	NR5A2 →	+0.631	+0.475	.003	.009	3	2
LSCC	MYCT1 →	+0.937	+0.585	.005	<.001	3	2
LUAD	ATP7B →	+0.992	+0.596	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,212 associations by consensus.

C1orf56 vs SEMA3G — BRCA

Explore this scatter interactively →