C1orf54

Across TCGA patient cohorts, C1orf54 protein abundance is significantly associated with the RNA expression of many other genes, with 144 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C1orf54-associated genes across cancer lineages are MMP9, CHRAC1, and GARS1. Each is linked with C1orf54 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf54-to-partner and partner-to-C1orf54 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf54 versus MMP9 in GBM, with a Pearson correlation of -0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf54→partner) and Y-score (partner→C1orf54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MMP9 →	-4.993	-0.436	.005	.004	2	1
GBM	CHRAC1 →	+0.424	+0.393	.004	.005	2	1
GBM	GARS1 →	-0.689	-0.421	.001	.001	2	1
GBM	CEP41 →	-0.896	-0.539	.003	.002	2	1
GBM	MRPL32 →	-0.992	-0.421	<.001	.001	2	1
GBM	TPI1 →	-0.877	-0.421	.006	.001	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 144 associations by consensus.

C1orf54 vs MMP9 — GBM

Explore this scatter interactively →