C1orf54

Across TCGA patient cohorts, C1orf54 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1orf54-associated genes across cancer lineages are CD8+ T-cells, CD8+ Tcm, and Macrophages. Each is linked with C1orf54 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf54-to-partner and partner-to-C1orf54 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by C1orf54-low versus C1orf54-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf54→partner) and Y-score (partner→C1orf54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ T-cells →	+0.026	+3.845	.002	.004	3	1
UCEC	CD8+ Tcm →	+0.049	+2.935	<.001	.046	3	1
UCEC	Macrophages →	+0.024	+3.809	.019	.005	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD8+ T-cells by C1orf54 expression — UCEC

Explore this box plot interactively →