Across TCGA patient cohorts, C1orf53 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,851 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible C1orf53-associated proteins across cancer lineages are RPRD2, UBAP2L, and CDC73. Each is linked with C1orf53 in more than 4 cancer types. Because this analysis shows association rather than direction, both C1orf53-to-partner and partner-to-C1orf53 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf53→partner) and Y-score (partner→C1orf53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RPRD2 →	+0.291	+0.786	.001	<.001	3	5
LUAD	UBAP2L →	+0.225	+0.759	<.001	<.001	3	5
LSCC	CDC73 →	+0.317	+0.817	<.001	<.001	3	5
OV	NUCKS1 →	+0.497	+0.785	.002	.001	3	4
GBM	PIH1D1 →	+0.220	+0.424	.003	.008	3	4
GBM	C1orf35 →	+0.348	+0.488	<.001	.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,851 associations by consensus.

Exploration

C1orf53 survival (RNA) · tumor vs normal (RNA) · all C1orf53 data types