Across TCGA cell cohorts, C1orf53 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,806 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C1orf53-associated GO terms across cancer lineages are Electron transport chain, ATP synthesis coupled electron transport, and Mitochondrial ATP synthesis coupled electron transport. Each is linked with C1orf53 in more than 8 cancer types. Because this analysis shows association rather than direction, both C1orf53-to-partner and partner-to-C1orf53 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf53→partner) and Y-score (partner→C1orf53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Electron transport chain →	+0.078	+1.076	<.001	.003	3	9
OESOPHAGUS	ATP synthesis coupled electron transport →	+0.116	+1.476	.009	.002	3	9
OESOPHAGUS	Mitochondrial ATP synthesis coupled electron transport →	+0.116	+1.476	.009	.002	3	9
KIDNEY	Ribonucleoside triphosphate biosynthetic process →	+0.074	+0.855	.002	.002	3	9
OESOPHAGUS	Aerobic electron transport chain →	+0.118	+1.476	.007	.002	3	8
OESOPHAGUS	Respiratory electron transport chain →	+0.109	+1.476	.007	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,806 associations by consensus.

Exploration

C1orf53 survival (RNA) · tumor vs normal (RNA) · all C1orf53 data types