C1orf52

Across TCGA patient cohorts, C1orf52 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,407 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible C1orf52-associated proteins across cancer lineages are HTATIP2, ACSF3, and MAN2A1. Each is linked with C1orf52 in more than 4 cancer types. Because this analysis shows association rather than direction, both C1orf52-to-partner and partner-to-C1orf52 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf52 versus HTATIP2 in UCEC, with a Pearson correlation of -0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf52→partner) and Y-score (partner→C1orf52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HTATIP2 →	-0.612	-0.323	<.001	<.001	3	5
CCRCC	ACSF3 →	-0.323	-0.291	<.001	<.001	3	5
GBM	MAN2A1 →	-0.417	-0.267	<.001	<.001	3	4
LUAD	PKN2 →	+0.211	+0.275	.002	.004	3	4
LSCC	GNL1 →	+0.293	+0.354	<.001	<.001	3	4
BRCA	SPCS3 →	-0.438	-0.364	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,407 associations by consensus.

C1orf52 vs HTATIP2 — UCEC

Explore this scatter interactively →