C1orf52

Across TCGA patient cohorts, C1orf52 protein abundance is significantly associated with the RNA expression of many other genes, with 6,569 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C1orf52-associated genes across cancer lineages are DNA2, FANCI, and SASS6. Each is linked with C1orf52 in more than 4 cancer types. Because this analysis shows association rather than direction, both C1orf52-to-partner and partner-to-C1orf52 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf52 versus DNA2 in BRCA, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf52→partner) and Y-score (partner→C1orf52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DNA2 →	+0.797	+0.391	<.001	<.001	3	5
LSCC	FANCI →	+0.779	+0.235	<.001	<.001	3	5
LSCC	SASS6 →	+0.672	+0.271	<.001	<.001	3	5
LSCC	C18orf54 →	+0.668	+0.169	.002	.002	3	5
UCEC	POLQ →	+0.985	+0.231	<.001	<.001	3	5
LSCC	RAD54L →	+0.810	+0.260	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,569 associations by consensus.

C1orf52 vs DNA2 — BRCA

Explore this scatter interactively →