C1orf52

Across TCGA patient cohorts, C1orf52 mutation is significantly associated with the RNA expression of many other genes, with 619 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1orf52-associated genes across cancer lineages are BTBD10, IMMP1L, and MTA2. Each is linked with C1orf52 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf52-to-partner and partner-to-C1orf52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BTBD10 grouped by C1orf52-low versus C1orf52-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf52→partner) and Y-score (partner→C1orf52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BTBD10 →	+0.553	+2.627	.003	.006	3	1
UCEC	IMMP1L →	+0.538	+3.354	.001	.005	3	1
UCEC	MTA2 →	+0.422	+2.649	.008	.005	3	1
UCEC	EI24 →	+0.591	+3.459	.002	.005	3	1
UCEC	CHEK1 →	+0.642	+3.343	.009	.005	3	1
UCEC	SAP18 →	+0.340	+3.219	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 619 associations by consensus.

BTBD10 by C1orf52 expression — UCEC

Explore this box plot interactively →